GPR30 in brain microvasculature responds to bicarbonate, and its deficiency protects against ischemia-reperfusion injury, reducing neurological deficits and blood-brain barrier disruption. These ...
The primary renal response to respiratory alkalosis is to increase the excretion of bicarbonate (HCO3-) in the urine. Bicarbonate is a base, and its removal from the body helps to lower the blood pH.
Discovery of bicarbonate-sensing receptor offers therapeutic insights into ischemic stroke treatment
Researchers have identified this receptor in brain mural cells that regulates reperfusion injury. Optimal pH homeostasis for cellular function is maintained by the acid-base balance through multiple ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback